Endocannabinoid system - what is it?

The endocannabinoid system is a network of components within the human body that play an important role in our internal biological system.

He is responsible for regulating and balancing (homeostasis) the response of the human body to certain triggers. It influences, for example, appetite, metabolism, immunity changes, communication between cells of the human body and much more.

More importantly, the endocannabinoid system plays an important role in the physical and psychological effects of hemp on the human body.

Through this system, the active ingredients of hemp, called cannabinoids, react with your body's biological system and have a positive effect on these receptors.

Components of the endocannabinoid system

  • Cannabinoid receptors on the surface of the cell wall (Cannabinoid receptors are found on the surface of the cells - think of these receptors as a keyhole that only works if you put in the right key).
  • Endocannabinoids (Endocannabinoids are cannabinoids that naturally form the human body, neurotransmitters that are produced on the basis of the requirement of the endocannabinoid system when the body gives the signal that they are needed).
  • Enzymes (Enzymes play a very important role in the endocannabinoid system, they are responsible for the decomposition of the remainder of the endocannabinoid, once its physiological role has ended)

Functions of the endocannabinoid system

The endocannabinoid system is important for many basic functions of the human body, such as appetite, immune function, food metabolism, pain, sleep, memory, mood, digestion, inflammatory response, and more.

In addition to regulating these basic bodily functions, it also influences the physiological response to the disease.
A very good example is the treatment of cancer and the fight against cancer cells. Tumor cells have much more cannabinoid receptors than healthy cells and tissues of the human body.

There are also cases in which higher levels of endocannabinoids have been shown in humans suffering from arthritis, Parkinson's disease, anxiety or chronic pain.

Because of this, many scientists and medical researchers believe that the function of the endocannabinoid system is in homeostasis - the regulation of the body system and the maintenance of the balance of the internal environment in all circumstances.

The diseased body and condition are largely due to the inability of the body to achieve homeostasis. Therefore, the role of the endocannabinoid system and its maintenance of physical balance is of critical importance to medicine.

The endocannabinoid system is a real treasure for scientists and health experts. Although it is a complex system, it plays an important role in many body processes and it seems to have a promising potential in the targeted treatment of many diseases.

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Cannabidiol (CBD)

Cannabidiol, or CBD for short, naturally occurs in the tiny hair-like structures known as trichomes that grow on hemp. The first cannabinoid molecule discovered by 1940 has since been studied by researchers for the many health benefits of CBD. It has been shown that CBD promotes healthy sleep, relieves occasional joint pain, accelerates athletic recovery, promotes relaxation, improves mood, reduces stress and frustration, relieves occasional nausea, and supports immune health.

Cannabidiol exists in two states, CBD and CBD-a. Both are studied to discover their individual effects on the body. CBD-a, which grows directly on hemp, shows great potential for various types of treatment. However, its impact has not been as extensively researched as CBD. When CBD-a is heated to 120 ° C, it loses its acid chain in a process called decarboxylation (also called "activation") and becomes CBD. All our products undergo this process. CBD has been well studied and has a more pronounced effect than CBD-a due to the more efficient binding to the cannabidiol receptors of the body.

An organic product, CBD is a safe, natural alternative to synthetic options with little to no side effects. There has never been a recorded death in the millennia of hemp history. Although it has been shown that CBD is non-toxic even at extreme doses, you should consult your doctor

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CBD - is it psychoactive?

CBD is largely non-psychoactive, which means that it has no intoxicating effects. This has to do with how CBD interacts with cannabinoid receptors throughout the body. Like all cannabinoids and endocannabinoids, CBD acts in our endocannabinoid (ECS) system, which is part of the nervous system. The endocannabinoid system consists of cannabinoids that the body naturally produces, called endocannabinoids, and two primary cannabinoid receptors.

The first receptor, CB1, can be found mainly in the central nervous system (CNS). The other primary receptor, CB2, is found mainly in the entire peripheral nervous system (PNS), with smaller amounts found throughout the immune system, in the gastrointestinal system and in the central nervous system mentioned above.

Because CB1 receptors are mainly localized in the brain, they are responsible for the intoxicating effects of cannabinoids, while CB2 receptors are responsible for many other effects of cannabinoids in the body.

THC is psychoactive because it completely binds and activates the CB1 receptor. In addition, it completely binds and activates the CB2 receptor, leading to a number of other benefits that may result from THC uptake.

In comparison, CBD will bind to both the CB1 and CB2 receptors but will not show strong binding affinity to them. In the case of the CB1 receptor, this results in CBD providing some neurological benefits without psychoactive effects.

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Cannabinoids - what is it?

Cannabinoids are organic molecules that are naturally produced by hemp and that activate two receptors of the central nervous system of the body: CB1 and CB2. CB1 receptors are mainly in the brain, while CB2 receptors are distributed throughout the body. Because CBD does not activate the brain's CB1 receptors, it is largely non-psychoactive.

Each of the more than 100 known cannabinoids has unique receptor interactions that lead to individual results. Research has also shown that the benefits of cannabinoids multiply when used together, producing the so-called "entourage effect".

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