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Osteoporosis

Israeli researchers stated that the administration of THC and CBD to animals with broken bones stimulates the recovery process. "

Nearly 10 million Americans over the age of 50 have osteoporosis and 80% of them are women. Another 34 million Americans have a reduced amount of bone mass or osteopenia that predestines osteoporosis. A recent study reveals that the endocannabinoid system plays an important natural role in the formation of bone mass and raises the question of whether hemp can also play a role in the fight against osteoporosis.

The word osteoporosis means "bone loss" and is linked to the aging process. It is a condition when our bones lose their minaralm matter circumference, become more fragile and begin to fracture. Any bone can be affected, but the hips and spine are the most vulnerable. It has been proven that one out of two women and one in four men suffer breakage due to osteoporosis during 50 years.

Bisphosphonate medications such as Boniva, Fosamax, Reclast and Actonel are commonly prescribed for the prevention and treatment of osteoporosis. However, they have side effects, mostly malaise, stomach irritation and pharyngitis. In addition, some patients feel bone, joint and muscle pain, cardiac arrhythmia and rarely occurs osteonecrosis (bone damage) of the jaw called effect. On the 11. January 2011 issued a warning to the FDA about these drugs. It appears that taking these medicines over a five-year period can make the bones too brittle, which can cause bone fractures even without previous damage.

 

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In view of the serious side effects of prescription drugs, of course, a safe alternative is needed. In a normal bone, there is a balance between the osteoblasts (bone-forming cells) and the osteoclasts (bone-filling cells). As we age, the osteoblasts do not keep up with the osteoclasts, leading to osteoporosis. More recently, the main components of the endocannabinoid system (ECS), including the CB1 and CB2 receptors, and the 2 major endocannabinoids (anandamine and 2-AG), have been discovered in the spine and are involved in bone metabolism (metabolism). A lack of CB1 receptors in old mice causes age-related osteoporosis due to a high increase in bone loss and a decrease in bone formation, leading to an accumulation of fat cells in the bone marrow.

The CB2 receptors are located in the osteoblasts and osteoclasts and their activity supports bone formation and slows their disintegration. A lack of CB2 receptors in mice accelerated age-related bone loss. But activation of CB2 receptors reduces bone loss by delaying bone loss and enhancing bone formation. In view of the understanding of the role of ECS in bone formation, researchers believe that the external cannabinoids (natural or synthetic) become a drug for osteoporosis. In fact, a researcher in Israel discovered that administering THC and CBD to fractured mice stimulated the recovery process.

In summary, it appears that taking hemp or cannabinoids for prevention of osteoporosis may be a safer and more effective treatment than the usual drugs. In addition, the healing process of bone fractures can be improved by hemp.

 

 

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